In a new Surgeon General’s Advisory, U.S. Surgeon General Dr. Vivek Murthy warns about the public health crisis that loneliness, isolation, and disconnection pose to the American public. This Resource Library supports the Advisory by outlining recommendations and useful resources to support different stakeholder groups in the United States implement the Framework for a National Strategy to Advance Social Connection. Individuals and organizations can use this framework to address the public health problem of social disconnection and strengthen social connection. The recommendations and resources outlined in this Resource Library can also help stakeholders around the world combat loneliness and promote social connection in their own contexts.